RAP1A Human shRNA Plasmid Kit (Locus ID 5906)
Specifications
| Product Data | |
| Locus ID | 5906 |
|---|---|
| Synonyms | C21KG; G-22K; KREV-1; KREV1; RAP1; SMGP21 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | RAP1A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5906). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001010935, NM_001291896, NM_002884, NM_001010935.1, NM_001010935.2, NM_002884.1, NM_002884.2, NM_002884.3, NM_001291896.1, BC014086, BC014086.2, NM_001370216, NM_001370217 |
| UniProt ID | P62834 |
| Summary | This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. provided by RefSeq, May 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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