GRF2 (RAPGEF1) Human shRNA Plasmid Kit (Locus ID 2889)
Specifications
| Product Data | |
| Locus ID | 2889 |
|---|---|
| Synonyms | C3G; GRF2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | RAPGEF1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2889). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001304275, NM_005312, NM_198679, NM_198679.1, NM_005312.1, NM_005312.3, BC041710, NM_198679.2, NM_005312.4 |
| UniProt ID | Q13905 |
| Summary | This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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