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RFX1 Human shRNA Plasmid Kit (Locus ID 5989)

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SKU
TR309857
RFX1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 5989
Synonyms EFC; RFX
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components RFX1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5989). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_002918, NM_002918.1, NM_002918.2, NM_002918.3, NM_002918.4, BC049826, BC049826.1, BM557928, BM662273
UniProt ID P22670
Summary This gene encodes a member of the regulatory factor X (RFX) family of transcription factors, which are characterized by a winged-helix DNA-binding domain. The encoded transcription factor contains an N-terminal activation domain and a C-terminal repression domain, and may activate or repress target gene expression depending on cellular context. This transcription factor has been shown to regulate a wide variety of genes involved in immunity and cancer, including the MHC class II genes and genes that may be involved in cancer progression. This gene exhibits altered expression in glioblastoma and the autoimmune disease systemic lupus erythematosis (SLE). provided by RefSeq, Jul 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

SC-2001 Overcomes STAT3-mediated Sorafenib Resistance through RFX-1/SHP-1 Activation in Hepatocellular Carcinoma
Su, Tseng, Wu et al
Neoplasia (2014)
Cited by 46
AI Summary: OriGene products contributed to this study by providing control and shRNA plasmids used for gene knockdown experiments to investigate the role of RFX-1 in sorafenib resistance in hepatocellular carcinoma.
Snippet: 1.5 μg/ml puromycin for 2 weeks. Cells were routinely maintained under constant culture conditions. Control and shRNA plasmids were purchased from Origene. STAT3 Reporter Assay. Huh7 R1 and R3 cells were seeded in ... Cite SaveSaving
Showing 1-1 of 1 papers.
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