EMAP II (AIMP1) Human shRNA Plasmid Kit (Locus ID 9255)
Specifications
| Product Data | |
| Locus ID | 9255 |
|---|---|
| Synonyms | EMAP2; EMAPII; HLD3; p43; SCYE1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | AIMP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9255). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001142415, NM_001142416, NM_004757, NM_004757.1, NM_004757.2, NM_004757.3, NM_001142415.1, NM_001142416.1, BC014051, BC014051.2, BM314663, NM_001142416.2 |
| UniProt ID | Q12904 |
| Summary | The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. provided by RefSeq, Dec 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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