SEC24D Human shRNA Plasmid Kit (Locus ID 9871)
Specifications
| Product Data | |
| Locus ID | 9871 |
|---|---|
| Synonyms | CLCRP2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SEC24D - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9871). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001318066, NM_014822, NM_014822.1, NM_014822.2, NM_014822.3, BC035761, BC035761.1, BC037736, NM_014822.4 |
| UniProt ID | O94855 |
| Summary | The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Dec 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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