SGCE Human shRNA Plasmid Kit (Locus ID 8910)
Specifications
| Product Data | |
| Locus ID | 8910 |
|---|---|
| Synonyms | DYT11; epsilon-SG; ESG |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SGCE - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8910). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001099400, NM_001099401, NM_001301139, NM_003919, NM_001346713, NM_001346715, NM_001346717, NM_001346719, NM_001346720, NM_003919.1, NM_003919.2, NM_001099400.1, NM_001099401.1, NM_001301139.1, BC021709, BC021709.2, NM_001362809, NM_001362807, NM_001362808, NM_001301139.2, NM_001099401.2, NM_001099400.2, NM_003919.3 |
| UniProt ID | O43556 |
| Summary | This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2. provided by RefSeq, Oct 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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