SLIT2 Human shRNA Plasmid Kit (Locus ID 9353)
Specifications
| Product Data | |
| Locus ID | 9353 |
|---|---|
| Synonyms | SLIL3; Slit-2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SLIT2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9353). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001289135, NM_001289136, NM_004787, NM_004787.1, NM_004787.2, NM_004787.3, NM_001289136.1, NM_001289136.2, NM_001289135.1, NM_001289135.2, BC117190, BC143978, BM474839, NM_001289136.3, NM_001289135.3, NM_004787.4 |
| UniProt ID | O94813 |
| Summary | This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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