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SOX9 Human shRNA Plasmid Kit (Locus ID 6662)

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SKU
TR309170
SOX9 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 6662
Synonyms CMD1; CMPD1; SRA1; SRXX2; SRXY10
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components SOX9 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 6662). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_000346, NM_000346.1, NM_000346.2, NM_000346.3, BC056420, BC056420.1, BC007951, BC018276, NM_000346.4
UniProt ID P48436
Summary The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Oncogenicity of the developmental transcription factor Sox9
Matheu, Collado, Wise et al
Cancer Res. (2012) 72 (5), 1301-15 DOI: 10.1158/0008-5472.CAN-11-3660
Cited by 14
AI Summary: OriGene’s SOX9 shRNAs (sh1 and sh75) were used to knock down SOX9 expression in cells, enabling the authors to study the effects of SOX9 depletion on tumorigenic properties in their investigation of SOX9’s role in cancer.
Snippet: by short hairpin RNA (shRNA), cells were transfected using Lipofectamine (Invitrogen), according to instructions of the reagent supplier. Cells were cultivated in the presence of puromycin for 3 weeks. Cells were transfected using 2 different SOX9 shRNAs (OriGene;sh1 or sh75
Showing 1-1 of 1 papers.
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