SUPV3L1 Human shRNA Plasmid Kit (Locus ID 6832)
Specifications
| Product Data | |
| Locus ID | 6832 |
|---|---|
| Synonyms | SUV3 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SUPV3L1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 6832). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001301683, NM_001323584, NM_001323585, NM_001323586, NM_001323587, NM_001323588, NM_003171, NR_136626, NR_136627, NM_003171.1, NM_003171.2, NM_003171.3, NM_003171.4, NM_001301683.1, BC036112, BC036112.1, BM675613, NM_001301683.2, NM_003171.5 |
| UniProt ID | Q8IYB8 |
| Summary | Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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