TFPI Human shRNA Plasmid Kit (Locus ID 7035)

SKU
TR308862
TFPI - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 7035
Synonyms EPI; LACI; TFI; TFPI1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components TFPI - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 7035). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC015514, NM_001032281, NM_001318941, NM_006287, NM_001329239, NM_001329240, NM_001329241, NM_001032281.1, NM_001032281.2, NM_001032281.3, NM_006287.2, NM_006287.3, NM_006287.4, NM_006287.5, BC015514.1, BC014332, NM_006287.6
UniProt ID P10646
Summary This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. provided by RefSeq, Jul 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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