OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

TLR5 Human shRNA Plasmid Kit (Locus ID 7100)

Be the first to review this product
SKU
TR308792
TLR5 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

Frequently Bought Together (2)

TA337067 Mouse Monoclonal TLR5 Antibody (19D759.2)
100 ug
$585.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "TLR5 or NM_003268"

Specifications
Specifications
Product Data
Locus ID 7100
Synonyms MELIOS; SLE1; SLEB1; TIL3
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components TLR5 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 7100). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_003268, NM_003268.2, NM_003268.3, NM_003268.4, NM_003268.5, BC109118, BC109119, NM_003268.6
UniProt ID O60602
Summary This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.provided by RefSeq, Dec 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis
Pal, Daniels, Oskman et al
MBio (2016) 7 (3) DOI: 10.1128/mBio.00617-16
AI Summary: OriGene products contributed to this study by providing shRNAs targeting Myd88 (TG311320), NFκB (TR318700), caspase-1 (TG305640), TLR9 (TR301076), TLR5 (TR308792), and TLR2 (TR320553), which were used to investigate the molecular pathways involved in HRPII-induced disruption of brain endothelial barriers.
Snippet: Cells were then incubated for 36 h. HRPII was then added, and TEER measurements were recorded over 24 h. shRNAs for each gene were purchased from Origene as follows: for the Myd88 gene, TG311320;for the NFκB gene, TR318700;for the caspase-1 gene, TG305640;for the TLR9 gene, TR301076;for the TLR5 gene, TR308792;and for the TLR2 gene, TR320553
The Role of Histidine Rich Protein II in Cerebral Malaria
Pal
Thesis (2017)
Snippet: …shRNAs for each gene were purchased from Origene : Myd88 (TG311320), NFкB (TR318700), Caspase-1 (TG305640), TLR9 (TR301076), TLR5 (TR308792), TLR2 (TR320553);of the four shRNAs received from the vendor, 2-3 were used based on silencing efficiency in pilot studies
The Role of Histidine Rich Protein II in Cerebral Malaria Pathogenesis
Pal
Thesis (2017)
Snippet: shRNAs for each gene were purchased from Origene : Myd88 (TG311320), NFB (TR318700), Caspase-1 (TG305640), TLR9 (TR301076), TLR5 (TR308792), TLR2 (TR320553);of the four shRNAs received from the vendor, 2-3 were used based on silencing efficiency ... Cite SaveSaving
Showing 1-3 of 3 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products