DR4 (TNFRSF10A) Human shRNA Plasmid Kit (Locus ID 8797)
Specifications
| Product Data | |
| Locus ID | 8797 |
|---|---|
| Synonyms | APO2; CD261; DR4; TRAILR-1; TRAILR1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | TNFRSF10A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8797). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_003844, NM_003844.1, NM_003844.2, NM_003844.3, BC012866, BC012866.1 |
| UniProt ID | O00220 |
| Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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