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TULP1 Human shRNA Plasmid Kit (Locus ID 7287)

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SKU
TR308561
TULP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 7287
Synonyms LCA15; RP14; TUBL1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components TULP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 7287). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001289395, NM_003322, NM_003322.2, NM_003322.3, NM_003322.4, NM_003322.5, NM_001289395.1, BC032714, BC065261, NM_001289395.2, NM_003322.6
UniProt ID O00294
Summary This gene encodes a member of the tubby-like gene family (TULPs). Members of this family have been identified in plants, vertebrates, and invertebrates. TULP proteins share a conserved C-terminal region of approximately 200 amino acid residues. The protein encoded by this gene is thought to play a role in the physiology of photoreceptors. Mutations in this gene are associated with recessive juvenile retinitis pigmentosa and Leber congenital amaurosis-15. provided by RefSeq, Nov 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Tubby-like protein 1 (Tulp1) is a target of microRNA-134 and is down-regulated in experimental epilepsy
Rodriguez, Engel, Palfi et al
Int J Physiol Pathophysiol Pharmacol (2017) 9 (6), 178-187
Snippet: SH-SY5Y cell line was cultured in DMEM/F12 (Sigma-Aldrich) supplemented with 10% fetal bovine serum, 2 mM L-glutamine and 100 U/ml penicillin/streptomycin. SH-SY5Y cells were transfected with sh-Scramble or sh-Tulp1 expressing plasmid (Origene) using Metafectamine (Biontex) following the manufacturer’s protocol
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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