USPL1 Human shRNA Plasmid Kit (Locus ID 10208)
Specifications
| Product Data | |
| Locus ID | 10208 |
|---|---|
| Synonyms | bA121O19.1; C13orf22; D13S106E |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | USPL1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 10208). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001321532, NM_001321533, NM_001321534, NM_005800, NM_005800.1, NM_005800.2, NM_005800.3, NM_005800.4, BC038103, BC038103.2, BC012594, BC036027 |
| UniProt ID | Q5W0Q7 |
| Summary | SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms (PubMed:22878415). Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (PubMed:24413172). Is a component of complexes that can bind to U snRNA genes (PubMed:24413172).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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