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VAMP3 Human shRNA Plasmid Kit (Locus ID 9341)

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SKU
TR308442
VAMP3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 9341
Synonyms CEB
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components VAMP3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9341). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_004781, NM_004781.2, NM_004781.3, BC007050, BC007050.1, BC003570, BC005941, NM_004781.4
UniProt ID Q15836
Summary Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling TCRs to the immune synapse
Finetti, Patrussi, Galgano et al
J. Cell. Sci. (2015)
Cited by 71
AI Summary: OriGene’s shRNA constructs for human/mouse VAMP3 were used in this study to investigate the role of VAMP-3 in TCR recycling and its interaction with Rab8 during immune synapse assembly.
Snippet: Alcover and C. Hivroz), pmaxGFP, pJAF2.13 (IFT20GFP) (Follit et al., 2006) and pEGFP- mouse Smoothened (pEGFP-mSmo) (Addgene plasmid #25395) or shRNA constructs for human/mouse VAMP3 (OriGene Technologies, Inc) were used. Jurkat cells were transfected ... Cite SaveSaving
Showing 1-1 of 1 papers.
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