RBFOX1 Human shRNA Plasmid Kit (Locus ID 54715)

SKU
TR307579
RBFOX1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 54715
Synonyms 2BP1; A2BP1; FOX-1; FOX1; HRNBP1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components RBFOX1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 54715). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001142333, NM_001142334, NM_001308117, NM_018723, NM_145891, NM_145892, NM_145893, NM_145892.1, NM_145892.2, NM_145891.1, NM_145891.2, NM_145893.1, NM_145893.2, NM_018723.1, NM_018723.2, NM_018723.3, NM_001142334.1, NM_001142333.1, BC026312, BC033885, BC113691, BC143816, NM_001364800, NM_001142333.2, NM_145893.3, NM_145892.3, NM_018723.4, NM_145891.3
UniProt ID Q9NWB1
Summary The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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