RBFOX1 Human shRNA Plasmid Kit (Locus ID 54715)
Specifications
| Product Data | |
| Locus ID | 54715 |
|---|---|
| Synonyms | 2BP1; A2BP1; FOX-1; FOX1; HRNBP1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | RBFOX1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 54715). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001142333, NM_001142334, NM_001308117, NM_018723, NM_145891, NM_145892, NM_145893, NM_145892.1, NM_145892.2, NM_145891.1, NM_145891.2, NM_145893.1, NM_145893.2, NM_018723.1, NM_018723.2, NM_018723.3, NM_001142334.1, NM_001142333.1, BC026312, BC033885, BC113691, BC143816, NM_001364800, NM_001142333.2, NM_145893.3, NM_145892.3, NM_018723.4, NM_145891.3 |
| UniProt ID | Q9NWB1 |
| Summary | The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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