PUS10 Human shRNA Plasmid Kit (Locus ID 150962)
Specifications
| Product Data | |
| Locus ID | 150962 |
|---|---|
| Synonyms | CCDC139; DOBI; Hup10 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PUS10 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 150962). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_144709, NM_001322123, NM_001322124, NM_001322127, NM_144709.1, NM_144709.2, NM_144709.3, BC101680, BC101680.1, BC065197, BC101706, BC143480, NM_144709.4 |
| UniProt ID | Q3MIT2 |
| Summary | Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 PubMed 17900615).supplied by OMIM, May 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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