CLPB Human shRNA Plasmid Kit (Locus ID 81570)
Specifications
| Product Data | |
| Locus ID | 81570 |
|---|---|
| Synonyms | ANKCLB; HSP78; MEGCANN; MGCA7; SKD3 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CLPB - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 81570). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001258392, NM_001258393, NM_001258394, NM_030813, NM_030813.2, NM_030813.3, NM_030813.4, NM_030813.5, NM_001258394.1, NM_001258394.2, NM_001258393.1, NM_001258393.2, NM_001258392.1, NM_001258392.2, BC006404, BC006404.2, BC006257, NM_001258392.3, NM_030813.6, NM_001258393.3 |
| UniProt ID | Q9H078 |
| Summary | This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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