NEIL1 Human shRNA Plasmid Kit (Locus ID 79661)
SKU
TR307276
NEIL1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 79661 |
|---|---|
| Synonyms | FPG1; hFPG1; NEI1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | NEIL1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 79661). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC010876, NM_001256552, NM_024608, NR_046311, NM_001352519, NM_001352520, NM_024608.1, NM_024608.2, NM_024608.3, BC010876.1 |
| UniProt ID | Q96FI4 |
| Summary | This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Feb 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase
Muftuoglu, de Souza-Pinto, Dogan et al
J Biol Chem (2009) 284 (14), 9270-9 DOI: 10.1074/jbc.M807006200
Muftuoglu, de Souza-Pinto, Dogan et al
J Biol Chem (2009) 284 (14), 9270-9 DOI: 10.1074/jbc.M807006200
AI Summary: In this study, OriGene products—specifically, CSB shRNA (OriGene, Cat# TL313089) and NEIL1 shRNA (OriGene, Cat# TL313282)—were used to deplete CSB and NEIL1 in HeLa cells to investigate their roles in the repair of formamidopyrimidines, demonstrating that knockdown of these proteins strongly inhibited DNA repair.
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
