SH2B2 Human shRNA Plasmid Kit (Locus ID 10603)
Specifications
| Product Data | |
| Locus ID | 10603 |
|---|---|
| Synonyms | APS |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SH2B2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 10603). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_020979, NM_001359228, NM_001359229, NM_001359230, NM_001359231, NM_020979.1, NM_020979.2, NM_020979.3, NM_020979.4, NM_020979.5 |
| UniProt ID | O14492 |
| Summary | The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. provided by RefSeq, Jun 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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