CWC22 Human shRNA Plasmid Kit (Locus ID 57703)
Specifications
| Product Data | |
| Locus ID | 57703 |
|---|---|
| Synonyms | EIF4GL; fSAPb; NCM |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CWC22 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 57703). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_020943, NM_020943.1, NM_020943.2, BC093952, BC093952.1, BC016651, BC031216, BC041662, BC053573, BC057826, BC093954, BC143433, NM_020943.3 |
| UniProt ID | Q9HCG8 |
| Summary | Required for pre-mRNA splicing as component of the spliceosome (PubMed:12226669, PubMed:11991638, PubMed:22961380, PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961). Promotes exon-junction complex (EJC) assembly (PubMed:22959432, PubMed:22961380). Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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