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ADRM1 Human shRNA Plasmid Kit (Locus ID 11047)

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SKU
TR306807
ADRM1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Other products for "ADRM1 or NM_001281437"

Specifications
Specifications
Product Data
Locus ID 11047
Synonyms ARM-1; ARM1; GP110; PSMD16
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ADRM1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 11047). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001281437, NM_001281438, NM_007002, NM_175573, NM_175573.1, NM_175573.2, NM_007002.1, NM_007002.2, NM_007002.3, NM_001281437.1, NM_001281438.1, BC017245, BC017245.2, BC003059, BC010733, BC093021, BR000321, NM_007002.4
UniProt ID Q16186
Summary This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13)
Mazumdar, Gorgun, Sha et al
Proc Natl Acad Sci U S A (2010) 107 (31), 13854-9 DOI: 10.1073/pnas.0913495107
Cited by 70
AI Summary: In this study, OriGene’s ADRM1 (Rpn13) siRNA (SR300489) was used to knock down Rpn13 expression, enabling the authors to investigate its role in regulating NF-kappaB activity and inducible nitric oxide synthase (iNOS) degradation.
Showing 1-1 of 1 papers.
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