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ARID2 Human shRNA Plasmid Kit (Locus ID 196528)

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SKU
TR306601
ARID2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 196528
Synonyms BAF200; CSS6; p200
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ARID2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 196528). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_152641, NM_001347839, NM_152641.1, NM_152641.2, NM_152641.3, BC018661, BC038726, BC064625, BC090062, BC156211, BC172461, NM_152641.4
UniProt ID Q68CP9
Summary This gene encodes a member of the AT-rich interactive domain (ARID)-containing family of DNA-binding proteins. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and chromatin structure modification. This protein functions as a subunit of the polybromo- and BRG1-associated factor or PBAF (SWI/SNF-B) chromatin remodeling complex which facilitates ligand-dependent transcriptional activation by nuclear receptors. Mutations in this gene are associated with hepatocellular carcinomas. A pseudogene of this gene is found on chromosome1. provided by RefSeq, Dec 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression
Xu, Flowers, Moran
J. Biol. Chem. (2012) 287 (7), 5033-41 DOI: 10.1074/jbc.M111.279968
Cited by 3
AI Summary: OriGene’s ARID2 shRNA plasmids (pRS vectors containing ARID2 shRNA-encoding sequences) and scrambled control were used to stably deplete ARID2 in MC3T3-E1 cells, enabling the study of ARID2's role in tissue-specific gene expression during osteoblast differentiation.
Snippet: To generate stable ARID2-depleted cell lines, MC3T3-E1 cells were transfected with pRS vectors containing ARID2 shRNA-encoding sequences or a scrambled sequence purchased from OriGene (Rockville, MD) and selected with puromycin (4 μg/ml).
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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