ASCC2 Human shRNA Plasmid Kit (Locus ID 84164)
Specifications
| Product Data | |
| Locus ID | 84164 |
|---|---|
| Synonyms | ASC1p100; p100 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | ASCC2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 84164). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001242906, NM_032204, NM_032204.1, NM_032204.2, NM_032204.3, NM_032204.4, NM_001242906.1, BC025368, BC032760, NM_001369921, NM_001369922, NM_001369925, NM_001369926, NM_001369927, NM_001369930, NM_001369931, NM_001369936, NM_001369938, NM_001369939, NM_001369942, NM_001369945, NM_001369949, NM_001369920, NM_001369923, NM_001369924, NM_001369928, NM_001369929, NM_001369932, NM_001369933, NM_001369934, NM_001369935, NM_001369937, NM_001369940, NM_001369941, NM_001369943, NM_001369944, NM_001369946, NM_001369947, NM_001369948, NM_001369950, NM_001242906.2, NM_032204.5 |
| UniProt ID | Q9H1I8 |
| Summary | Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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