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B7-2 (CD86) Human shRNA Plasmid Kit (Locus ID 942)

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SKU
TR305507
CD86 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 942
Synonyms B7-2; B7.2; B70; CD28LG2; LAB72
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components CD86 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 942). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001206924, NM_001206925, NM_006889, NM_175862, NM_176892, NM_006889.1, NM_006889.2, NM_006889.3, NM_006889.4, NM_175862.1, NM_175862.2, NM_175862.3, NM_175862.4, NM_001206924.1, NM_001206925.1, NM_176892.1, BC040261
UniProt ID P42081
Summary This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.provided by RefSeq, May 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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