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CHCHD3 Human shRNA Plasmid Kit (Locus ID 54927)

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SKU
TR305418
CHCHD3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Other products for "CHCHD3 or NM_001317177"

Specifications
Specifications
Product Data
Locus ID 54927
Synonyms Mic19; MICOS19; MINOS3; PPP1R22
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components CHCHD3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 54927). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001317177, NM_017812, NR_133671, NM_001317178, NM_017812.1, NM_017812.2, NM_017812.3, BC011596, BC011596.2, BC014839, NM_017812.4
UniProt ID Q9NX63
Summary The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function
Darshi, Mendiola, Mackey et al
J. Biol. Chem. (2011) 286 (4), 2918-32 DOI: 10.1074/jbc.M110.171975
Cited by 52
AI Summary: OriGene’s Turbofectin transfection reagent was used in this study to deliver ChChd3-shRNA or scrambled-control constructs into cells, enabling the investigation of ChChd3’s role in mitochondrial structure and function.
Snippet: GlutaMAX grown to 40% confluency in 35 mm plates were transfected with ChChd3-shRNA or scrambled-control using Turbofectin (OriGene) according to ... To improve the signal-to-noise ratio, each image was binned down two times by averaging adjacent pixels so that the final
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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