DNASE2B Human shRNA Plasmid Kit (Locus ID 58511)
Specifications
| Product Data | |
| Locus ID | 58511 |
|---|---|
| Synonyms | DLAD |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | DNASE2B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 58511). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_021233, NM_058248, NM_021233.1, NM_021233.2, NM_058248.1, BC126136, BC065182, BC080621, BC126138 |
| UniProt ID | Q8WZ79 |
| Summary | The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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