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ERRFI1 Human shRNA Plasmid Kit (Locus ID 54206)

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SKU
TR304737
ERRFI1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Other products for "ERRFI1 or NM_018948"

Specifications
Specifications
Product Data
Locus ID 54206
Synonyms GENE-33; MIG-6; MIG6; RALT
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ERRFI1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 54206). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_018948, NM_018948.1, NM_018948.2, NM_018948.3, BC025337, BC025337.1, BC012839, NM_018948.4
UniProt ID Q9UJM3
Summary ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 PubMed 7641805). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 PubMed 10749885; Fiorentino et al., 2000 PubMed 11003669).supplied by OMIM, Mar 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

The induction of MIG6 under hypoxic conditions is critical for dormancy in primary cultured lung cancer cells with activating EGFR mutations
Endo, Okami, Okuyama et al
Oncogene (2016)
AI Summary: OriGene contributed to this study by providing shERRFI1 (#1 and #2) short hairpin RNA products, which were used to knock down MIG6 expression and investigate its role in hypoxia-induced dormancy and drug resistance in EGFR-mutant lung cancer cells.
Snippet: 53 The target sequences were as follows: shERRFI1 #1 and shERRFI1 #2 were purchased from OriGene (Rockville, MD, USA), shHIF1α: 5′-GACAGTACAGGATGCTTGC-3′, shHIF2α #1: 5′-GACAAGGTCTGCAAAGGGT-3′, shHIF2α #2: 5′-GGAGACGGAGGTGTTCTAT ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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