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EYA1 Human shRNA Plasmid Kit (Locus ID 2138)

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SKU
TR304716
EYA1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Other products for "EYA1 or NM_000503"

Specifications
Specifications
Product Data
Locus ID 2138
Synonyms BOP; BOR; BOS1; OFC1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components EYA1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2138). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_000503, NM_001288574, NM_001288575, NM_172058, NM_172059, NM_172060, NM_172059.1, NM_172059.2, NM_172059.3, NM_172060.1, NM_172060.2, NM_172060.3, NM_000503.1, NM_000503.2, NM_000503.3, NM_000503.4, NM_000503.5, NM_172058.1, NM_172058.2, NM_172058.3, NM_001288575.1, NM_001288574.1, BC121799, BC035138, BC048982, BC121798, NM_001370334, NM_001370335, NM_001370333, NM_001370336, NM_001288574.2, NM_000503.6, NM_001288575.2, NM_172058.4
UniProt ID Q99502
Summary This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Alternatively spliced transcript variants have been identified for this gene. provided by RefSeq, Dec 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

EYA1's conformation-specificity in dephosphorylating phosphothreonine in Myc and its activity on Myc stabilization in breast cancer
Li, Rodriguez, Cheng et al
Mol. Cell. Biol. (2016)
AI Summary: OriGene contributed to this study by providing shRNA expression plasmids for human EYA1 (TR304716) and control scramble shRNA, which were used to deplete EYA1 in breast cancer cells and assess its role in Myc protein stability.
Snippet: amino acid analysis and mass spectroscopy. The purity of each peptide was greaterthan 95%. shRNA expression plasmids for human EYA1 in a pRFP-C-RS vector and its controlscramble shRNA were purchased from OriGene (TR304716). They have been tested ... Cite SaveSaving
Regulation of the innate immune response by threonine-phosphatase of Eyes absent
Okabe, Sano, Nagata
Nature (2009) 460 (7254), 520-4 DOI: 10.1038/nature08138
Cited by 167
AI Summary: OriGene products, specifically the EYA4 expression plasmid (OriGene, MC205779) and EYA4 shRNA (OriGene, TG313747), were used in this study to manipulate EYA4 levels in cells, enabling the authors to investigate the role of EYA4 in regulating the innate immune response to undigested DNA and viral infection.
Showing 1-2 of 2 papers.
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