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FOXP1 Human shRNA Plasmid Kit (Locus ID 27086)

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SKU
TR304471
FOXP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Other products for "FOXP1 or NM_001012505"

Specifications
Specifications
Product Data
Locus ID 27086
Synonyms 12CC4; hFKH1B; HSPC215; MFH; QRF1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components FOXP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 27086). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001012505, NM_001244808, NM_001244810, NM_001244812, NM_001244813, NM_001244814, NM_001244815, NM_001244816, NM_016477, NM_032682, NM_001349337, NM_001349338, NM_001349339, NM_001349340, NM_001349341, NM_001349342, NM_001349343, NM_001349344, NR_146142, NR_146143, NM_032682.1, NM_032682.2, NM_032682.3, NM_032682.4, NM_032682.5, NM_001012505.1, NM_001244813.1, NM_001244812.1, NM_001244808.1, NM_001244814.1, NM_001244816.1, NM_001244815.1, NM_001244810.1, BC005055, BC054505, BC054815, BC068481, BC071893, BC080521, BC131720, BC152752, NM_001370548, NM_001244812.3, NM_001244810.2, NM_001012505.2, NM_001244808.3, NM_001244813.3, NM_032682.6, NM_001244816.2, NM_001244814.3
UniProt ID Q9H334
Summary This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

FOXP1 is a key regulator of quiescence in healthy human CD3(+) CD4(+) T Cells and is constitutively repressed in CD3(-) CD4(+) T cells from patients with lymphoproliferative disorders
Garaud, Roufosse, De Silva et al
Eur. J. Immunol. (2016)
Cited by 38
AI Summary: OriGene's FOXP1 shRNA and scrambled shRNA products were used to transiently knock down FOXP1 expression in human CD4(+) T cells, enabling the study of FOXP1's role in regulating T cell quiescence and differentiation in this research.
Snippet: Constructs and transfection In the knock-down assay, total, naive and memory CD4+T cells (5x106 cells/well;12 well- plate) were transiently transfected with either 5g FOXP1 orscrambled shRNA (Origene, Rockville, MD, USA) using the Nucleofector device and ... Cite SaveSaving
Showing 1-1 of 1 papers.
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