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HNRNPC Human shRNA Plasmid Kit (Locus ID 3183)

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SKU
TR304074
HNRNPC - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Other products for "HNRNPC or NM_001077442"

Specifications
Specifications
Product Data
Locus ID 3183
Synonyms C1; C2; HNRNP; HNRPC; SNRPC
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components HNRNPC - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3183). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001077442, NM_001077443, NM_004500, NM_031314, NM_004500.1, NM_004500.2, NM_004500.3, NM_001077442.1, NM_031314.1, NM_031314.2, NM_001077443.1, BC003394, BC003394.1, BC007052, BC103758, BC103758.1, BC008364, BC008423, BC066932, BC071943, BC089438, BC092433, BC108658, NM_004500.4
UniProt ID P07910
Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

The RNA binding protein hnRNP Q modulates the utilization of exon 7 in the survival motor neuron 2 (SMN2) gene
Chen, Chang, Lu et al
Mol Cell Biol (2008) 28 (22), 6929-38 DOI: 10.1128/MCB.01332-08
AI Summary: OriGene products contributed to this study by providing the hnRNP Q1, Q2, and Q3 expression plasmids (OriGene catalog #RC206227, RC206228, and RC206229), which were used to assess the effects of different hnRNP Q isoforms on SMN2 exon 7 splicing.
FigureFigureFigure
Showing 1-1 of 1 papers.
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