HTRA3 Human shRNA Plasmid Kit (Locus ID 94031)

SKU
TR304012
HTRA3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 94031
Synonyms Prsp; Tasp
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components HTRA3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 94031). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001297559, NM_053044, NM_053044.1, NM_053044.2, NM_053044.3, NM_053044.4, NM_001297559.1, BC035717, BC035717.1, BC034390, NM_001297559.2, NM_053044.5
UniProt ID P83110
Summary Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (PubMed:21321049, PubMed:22229724).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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