IMPDH1 Human shRNA Plasmid Kit (Locus ID 3614)
Specifications
| Product Data | |
| Locus ID | 3614 |
|---|---|
| Synonyms | IMPD; IMPD1; IMPDH-I; LCA11; RP10; sWSS2608 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | IMPDH1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3614). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_000883, NM_001102605, NM_001142573, NM_001142574, NM_001142575, NM_001142576, NM_001304521, NM_183243, NM_183243.1, NM_183243.2, NM_000883.1, NM_000883.2, NM_000883.3, NM_001102605.1, NM_001142573.1, NM_001142574.1, NM_001142575.1, NM_001142576.1, BC033622, BC033622.1, NM_001142575.2, NM_001142573.2, NM_001142576.2, NM_001142574.2, NM_001102605.2, NM_183243.3, NM_000883.4 |
| UniProt ID | P20839 |
| Summary | The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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