LACE1 Human shRNA Plasmid Kit (Locus ID 246269)
Specifications
| Product Data | |
| Locus ID | 246269 |
|---|---|
| Synonyms | AFG1; c222389; LACE1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | LACE1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 246269). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_145315, NM_001323005, NR_136553, NM_145315.3, NM_145315.4, BC018445, BC018445.1, NM_145315.5 |
| UniProt ID | Q8WV93 |
| Summary | This gene encodes a mitochondrial integral membrane protein that plays a role in mitochondrial protein homeostasis. The protein contains a P-loop motif and a five-domain structure that is conserved in fly, yeast, and bacteria. It functions to mediate the degradation of nuclear-encoded complex IV subunits. Two conserved estrogen receptor binding sites are located within 2.5 kb of this gene. Polymorphisms in this gene have been associated with bipolar disorder. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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