LAS1L Human shRNA Plasmid Kit (Locus ID 81887)
Specifications
| Product Data | |
| Locus ID | 81887 |
|---|---|
| Synonyms | dJ475B7.2; Las1; Las1-like; WTS |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | LAS1L - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 81887). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001170649, NM_001170650, NM_031206, NM_031206.1, NM_031206.2, NM_031206.3, NM_031206.4, NM_001170650.1, NM_001170649.1, BC014545, BC014545.1, BC018610, BC019302, NM_031206.7 |
| UniProt ID | Q9Y4W2 |
| Summary | Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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