LRDD (PIDD1) Human shRNA Plasmid Kit (Locus ID 55367)
Specifications
| Product Data | |
| Locus ID | 55367 |
|---|---|
| Synonyms | DKFZp434D229; leucine-rich and death domain containing; leucine-rich repeats and death domain containing; leucine rich repeat and death domain containing protein; MGC16925; PIDD |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PIDD1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 55367). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_018494, NM_145886, NM_145887, NM_145887.1, NM_145887.2, NM_145887.3, NM_145886.1, NM_145886.2, NM_145886.3, NM_018494.3, BC014904, BC014904.1, NM_145887.4, NM_145886.4 |
| UniProt ID | Q9HB75 |
| Summary | The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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