MID1 Human shRNA Plasmid Kit (Locus ID 4281)

SKU
TR303260
MID1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 4281
Synonyms BBBG1; FXY; GBBB1; MIDIN; OGS1; OS; OSX; RNF59; TRIM18; XPRF; ZNFXY
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components MID1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4281). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_000381, NM_001098624, NM_001193277, NM_001193278, NM_001193279, NM_001193280, NM_001193281, NM_033289, NM_033290, NM_033291, NM_001347733, NM_000381.1, NM_000381.2, NM_000381.3, NM_033290.1, NM_033290.2, NM_033290.3, NM_001098624.1, NM_001098624.2, NM_001193281.1, NM_001193280.1, NM_001193279.1, NM_001193278.1, NM_033289.1, NM_001193277.1, NM_033291.1, BC053626, BC053626.1, NM_033290.4, NM_000381.4, NM_033289.2
UniProt ID O15344
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities. provided by RefSeq, Dec 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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