NMT1 Human shRNA Plasmid Kit (Locus ID 4836)
Specifications
| Product Data | |
| Locus ID | 4836 |
|---|---|
| Synonyms | NMT |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | NMT1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4836). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_021079, NM_021079.1, NM_021079.2, NM_021079.3, NM_021079.4, BC006538, BC006538.2, BC006569, BC007258, BC008312, BC008579, BC109226, NM_021079.5 |
| UniProt ID | P30419 |
| Summary | Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 PubMed 1570339).supplied by OMIM, Nov 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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