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PARD3 Human shRNA Plasmid Kit (Locus ID 56288)

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SKU
TR302678
PARD3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Other products for "PARD3 or NM_001184785"

Specifications
Specifications
Product Data
Locus ID 56288
Synonyms ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A; PPP1R118; SE2-5L16; SE2-5LT1; SE2-5T2
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PARD3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 56288). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001184785, NM_001184786, NM_001184787, NM_001184788, NM_001184789, NM_001184790, NM_001184791, NM_001184792, NM_001184793, NM_001184794, NM_019619, NM_019619.1, NM_019619.2, NM_019619.3, NM_001184794.1, NM_001184793.1, NM_001184792.1, NM_001184791.1, NM_001184790.1, NM_001184789.1, NM_001184788.1, NM_001184787.1, NM_001184786.1, NM_001184785.1, BC071566, BC011711, BM796605
UniProt ID Q8TEW0
Summary This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene. provided by RefSeq, Oct 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

The polarity protein Par3 enhances renal cell carcinoma metastasis via YAP/TAZ activation
Lee, Balcazar, Davis et al
Cancer Biol Med (2025) 22 (7), 812-31 DOI: 10.20892/j.issn.2095-3941.2024.0297
Cited by 1
AI Summary: OriGene’s shRNA-Par3 (TR302678) and sc control plasmid (TR30012) were used to generate stable Par3 knockdown cell lines, enabling the study of Par3’s role in promoting renal cell carcinoma metastasis via YAP/TAZ pathway activation.
Snippet: To create clone cell lines with stable Par3 knockdown (KD), we mixed shRNA-Par3 (Origene, TR302678, retroviral vector) or sc control plasmid (Origene, TR30012) with;ereas overexpression (OE) of Par3 decreases pancreatic cancer metastasis12;both effects have been shown to be associated with Par3 regulation of the TIAM/RAC1 signaling pathway. …
FigureFigureFigure
Elevated expression of Par3 promotes prostate cancer metastasis by forming a Par3/aPKC/KIBRA complex and inactivating the hippo pathway
Zhou, Xue, Peng et al
J. Exp. Clin. Cancer Res. (2017) 36 (1), 139 DOI: 10.1186/s13046-017-0609-y
AI Summary: OriGene contributed Par3 knockdown and control plasmids, which were used to manipulate Par3 expression in prostate cancer cells and investigate its role in cancer metastasis.
Snippet: C. Cell transfection and lentiviral vector infection. The Par3 knock down and control plasmids were obtained from Origene (Rockville, MD, USA). Plasmids were transfected with Lipofectamine3000 (Thermo Fisher Scientific). ... Cached;... C. Cell transfection and lentiviral vector infection. The Par3 knock down and control plasmids were obtained from Origene (Rockville, MD, USA). Plasmids were t...
FigureFigureFigure
Showing 1-2 of 2 papers.
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