PGPEP1 Human shRNA Plasmid Kit (Locus ID 54858)
Specifications
| Product Data | |
| Locus ID | 54858 |
|---|---|
| Synonyms | PAP-I; Pcp; PGI; PGP; PGP-I; PGPI |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PGPEP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 54858). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC042138, NM_001300927, NM_001308366, NM_001329471, NM_001329476, NM_001329477, NM_001329478, NM_017712, NR_138029, NM_017712.1, NM_017712.2, NM_017712.3, NM_001300927.1, BC042138.1, BC004942, BC028063, NM_017712.4, NM_001300927.2 |
| UniProt ID | Q9NXJ5 |
| Summary | The gene encodes a cysteine protease and member of the peptidase C15 family of proteins. The encoded protein cleaves amino terminal pyroglutamate residues from protein substrates including thyrotropin-releasing hormone and other neuropeptides. Expression of this gene may be downregulated in colorectal cancer, while activity of the encoded protein may be negatively correlated with cancer progression in colorectal cancer patients. Activity of the encoded protease may also be altered in other disease states including in liver cirrhosis, which is associated with reduced protease activity, and in necrozoospermia, which is associated with elevated protease activity. provided by RefSeq, Jul 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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