PLA2G3 Human shRNA Plasmid Kit (Locus ID 50487)
Specifications
| Product Data | |
| Locus ID | 50487 |
|---|---|
| Synonyms | GIII-SPLA2; sPLA2-III; SPLA2III |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PLA2G3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 50487). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_015715, NM_015715.1, NM_015715.2, NM_015715.3, NM_015715.4, BC025316, BC025316.1, NM_015715.5 |
| UniProt ID | Q9NZ20 |
| Summary | This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. provided by RefSeq, Apr 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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