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PPP2R2B Human shRNA Plasmid Kit (Locus ID 5521)

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SKU
TR302320
PPP2R2B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Other products for "PPP2R2B or NM_001127381"

Specifications
Specifications
Product Data
Locus ID 5521
Synonyms B55BETA; PP2AB55BETA; PP2ABBETA; PP2APR55B; PP2APR55BETA; PR2AB55BETA; PR2ABBETA; PR2APR55BETA; PR52B
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PPP2R2B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5521). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001127381, NM_001271899, NM_001271900, NM_001271948, NM_004576, NM_181674, NM_181675, NM_181676, NM_181677, NM_181678, NR_073526, NR_073527, NM_181675.1, NM_181675.2, NM_181675.3, NM_181677.1, NM_181677.2, NM_181678.1, NM_181678.2, NM_181674.1, NM_181674.2, NM_181676.1, NM_181676.2, NM_001271948.1, NM_001271899.1, NM_001271900.1, NM_001127381.1, NM_004576.2, BC031790, BC031790.1, NM_001271900.2, NM_181675.4
UniProt ID Q00005
Summary The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12. provided by RefSeq, Jul 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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