PSG2 Human shRNA Plasmid Kit (Locus ID 5670)
Specifications
| Product Data | |
| Locus ID | 5670 |
|---|---|
| Synonyms | CEA; PSBG2; PSG1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PSG2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5670). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_031246, NM_031246.1, NM_031246.2, NM_031246.3, BC022316, BC022316.1, NM_031246.4 |
| UniProt ID | P11465 |
| Summary | The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 PubMed 7851896). For additional general information about the PSG gene family, see PSG1 (MIM 176390).supplied by OMIM, Oct 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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