CtIP (RBBP8) Human shRNA Plasmid Kit (Locus ID 5932)
Specifications
| Product Data | |
| Locus ID | 5932 |
|---|---|
| Synonyms | COM1; CTIP; JWDS; RIM; SAE2; SCKL2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | RBBP8 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5932). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_002894, NM_203291, NM_203292, NM_203292.1, NM_203291.1, NM_002894.2, BC001170, BC030590, NM_002894.3 |
| UniProt ID | Q99708 |
| Summary | The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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