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RHBDF1 Human shRNA Plasmid Kit (Locus ID 64285)

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SKU
TR302009
RHBDF1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 64285
Synonyms C16orf8; Dist1; EGFR-RS; gene-89; gene-90; hDist1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components RHBDF1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 64285). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_022450, NM_022450.1, NM_022450.2, NM_022450.3, BC014425, BC014425.1, BM830007
UniProt ID Q96CC6
Summary Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Human rhomboid family-1 modulates clathrin coated vesicle-dependent pro-transforming growth factor α membrane trafficking to promote breast cancer progression
Li, Bai, Gao et al
EBioMedicine (2018) 36, 229-240 DOI: 10.1016/j.ebiom.2018.09.038
AI Summary: OriGene’s pRS Vector containing scrambled shRNA cassette was used to generate control breast cancer cell lines for comparison in experiments investigating the role of RHBDF1 in pro-TGFα membrane trafficking and breast cancer progression.
Snippet: were generated, respectively (Fig. S1A), by using shRNA constructs in retroviral vector or scrambled shRNA cassette in pRS Vector (Origene), and selected with puromycin for 2 months. RHBDF1-overexpressing (RHB) and
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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