RNF128 Human shRNA Plasmid Kit (Locus ID 79589)
Specifications
| Product Data | |
| Locus ID | 79589 |
|---|---|
| Synonyms | GRAIL |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | RNF128 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 79589). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_024539, NM_194463, NM_194463.1, NM_024539.1, NM_024539.2, NM_024539.3, BC063404, BC063404.1, BC012931, BC030951, BC036901, BC056677, NM_194463.2 |
| UniProt ID | Q8TEB7 |
| Summary | The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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