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RTN3 Human shRNA Plasmid Kit (Locus ID 10313)

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SKU
TR301880
RTN3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 10313
Synonyms ASYIP; HAP; NSPL2; NSPLII; RTN3-A1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components RTN3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 10313). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001265589, NM_001265590, NM_001265591, NM_006054, NM_201428, NM_201429, NM_201430, NR_049750, NR_049751, NM_006054.1, NM_006054.2, NM_006054.3, NM_201429.1, NM_201429.2, NM_201430.1, NM_201430.2, NM_201428.1, NM_201428.2, NM_001265591.1, NM_001265590.1, NM_001265589.1, BC000634, BC000865, BC010556, BC011394, BC022993, BC100822, BC100823, BC105981, BC105982, BC118550, BC118628, BC148632, NM_006054.4, NM_001265589.2, NM_001265590.2, NM_201430.3, NM_001265591.2, NM_201428.3
UniProt ID O95197
Summary This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. provided by RefSeq, May 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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