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SECISBP2 Human shRNA Plasmid Kit (Locus ID 79048)

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SKU
TR301785
SECISBP2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 79048
Synonyms SBP2
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components SECISBP2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 79048). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC001189, NM_001282688, NM_001282689, NM_001282690, NM_024077, NM_001354696, NM_001354697, NM_001354698, NM_001354702, NM_024077.1, NM_024077.2, NM_024077.3, NM_024077.4, NM_001282689.1, NM_001282690.1, NM_001282688.1, BC001189.1, BC036109, BC036109.1, BC023142, BC068466, BC099900, BM666620, NM_001282689.2, NM_001282688.2, NM_024077.5
UniProt ID Q96T21
Summary The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Aug 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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