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SENP7 Human shRNA Plasmid Kit (Locus ID 57337)

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SKU
TR301771
SENP7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 57337
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components SENP7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 57337). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001077203, NM_001282801, NM_001282802, NM_001282803, NM_001282804, NM_020654, NM_020654.1, NM_020654.3, NM_020654.4, NM_001077203.1, NM_001077203.2, NM_001282804.1, NM_001282803.1, NM_001282801.1, NM_001282802.1, BC129988, BC039900, BC062674, NM_001282802.2, NM_001282803.2, NM_001077203.3, NM_001282801.2, NM_020654.5
UniProt ID Q9BQF6
Summary The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 PubMed 18799455).supplied by OMIM, Jun 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Novel SUMO-Protease SENP7S Regulates β-catenin Signaling and Mammary Epithelial Cell Transformation
Karami, Lin, Kumar et al
Sci Rep (2017) 7, 46477 DOI: 10.1038/srep46477
AI Summary: OriGene products contributed to this study by providing the shRNA vector used to generate SENP7S-targeting shRNA (shSENP7S) and the TissueScan Breast Cancer Survey II panel for assessing SENP7S mRNA levels in human patient samples.
Snippet: The SENP7S-siRNA oligo was integrated into a puromycin-selection shRNA vector (Origene) to generate SENP7S-targeting shRNA (shSENP7S). ... Real-time PCR. TissueScan Breast Cancer Survey II (Origene) was used for assessment of mRNA in human patient samples ... All 2 versions Cite SaveSaving
FigureFigureFigure
Showing 1-1 of 1 papers.
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