SLC39A14 Human shRNA Plasmid Kit (Locus ID 23516)
Specifications
| Product Data | |
| Locus ID | 23516 |
|---|---|
| Synonyms | cig19; HCIN; HMNDYT2; LZT-Hs4; NET34; ZIP14 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SLC39A14 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 23516). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001128431, NM_001135153, NM_001135154, NM_015359, NM_001351655, NM_001351656, NM_001351657, NM_001351658, NM_001351659, NM_001351660, NM_015359.1, NM_015359.2, NM_015359.3, NM_015359.4, NM_001135154.1, NM_001128431.1, NM_001128431.2, NM_001135153.1, BC015770, BC000068, NM_015359.6, NM_001128431.4, NM_001135153.3, NM_001135154.3 |
| UniProt ID | Q15043 |
| Summary | This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. provided by RefSeq, May 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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